The polyethylene glycol series products are non-toxic and non-irritating, have good water solubility, and have good compatibility with many organic components. They possess excellent lubricating properties, moisturizing properties, dispersing properties, adhesives, antistatic agents, and softening agents, etc. They are widely applied in industries such as cosmetics, pharmaceuticals, chemical fibers, rubber, plastics, papermaking, paints, electroplating, pesticides, metal processing, and food processing.
Specification
|
Item |
PEG4000 |
Standard |
|
Appearance |
White solid |
/ |
|
OH Value, mgKOH/g |
25-28 |
GB/T 7383-2007 |
|
Moisture, (%) |
<=0.5 |
GB/T 11275-2007 |
|
pH |
5.0-7.0 |
GB/T 6368-2008 |
|
Chroma (AHPH) |
<=50 |
GB/T 9282.1-2008S50 |
Properties of polyethylene glycol
A polymer formed by the addition reaction of polyethylene and water. Those with a molecular weight below 700 are colorless, odorless, non-volatile viscous liquids at 20℃, slightly hygroscopic. Those with a molecular weight between 700 and 900 are semi-solid. Those with a molecular weight of 1000 or above are pale white waxy solids or flocculent paraffin or flowable powders. It is miscible with water and soluble in many organic solvents such as alcohols, ketones, glycerides, and aromatic hydrocarbons; it is insoluble in most aliphatic hydrocarbons. As the molecular weight increases, its water solubility, vapor pressure, hygroscopicity, and solubility in organic solvents all decrease accordingly, while the freezing point, relative density, flash point, and viscosity increase accordingly. It is heat stable, does not react with many chemicals, and does not hydrolyze.
Applications in Molecular Biology
PEG can induce the aggregation of macromolecules in aqueous solutions. It has many applications in molecular cloning, including: 1. Precipitating DNA by size; 2. Precipitating and purifying phage particles; 3. During hybridization, DNA molecular blunt-end ligation, and DNA terminal labeling using T4 polynucleotide kinase, it increases the binding efficiency of complementary nucleic acid chains. 4. Fusion of cells or bacterial protoplasts.


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